l General Information |
Product Name | Sertraline HCl |
General description | Sertraline HCl is a 5-HT antagonist with Ki of 13 nM. |
Synonym | CP-51974-1 HCl; (1S,4S)-4-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrahydronaphthalen-1-amine; hydrochloride |
Purity | ≥99.0%(HPLC) | CAS Number | 79559-97-0 |
Formula | C17H18Cl3N | Molecular Weight | 342.688 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | White to off-white Solid |
Solubility(25°C) | DMSO | ≥45mg/ml |
Ethanol | ~5mg/ml |
Water | Very slightly soluble |
l Biological Information |
Biochem/Physiol
Actions | Sertraline Hydrochloride is the hydrochloride salt of sertraline, a synthetic derivative of naphthalenamine with anti-serotoninergic and anti-depressant properties. Sertraline appears to selectively inhibit the neuronal uptake of serotonin, raising serotonin levels in the CNS. |
l Storage |
Storage temp. | -20°C |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
