l General Information |
Product Name | Pemirolast potassium |
General description | Pemirolast potassium is a histamine H1 antagonist and mast cell stabilizer that acts as an antiallergic agent. |
Synonym | BMY26517; potassium;9-methyl-3-(1,2,3-triaza-4-azanidacyclopenta-2,5-dien-5-yl)pyrido[1,2-a]pyrimidin-4-one |
Purity | ≥98.0%(HPLC) | CAS Number | 100299-08-9 |
Formula | C10H7KN6O | Molecular Weight | 266.305 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | Light Yellow to Green-Yellow Solid |
Solubility(25°C) | DMSO | Insoluble |
Ethanol | Insoluble |
Water | ≥45mg/mL |
l Biological Information |
Biochem/Physiol
Actions | Pemirolast Potassium is the potassium salt form of pemirolast, a pyrimidinone derivative with antiallergic property. Pemirolast potassium exerts its action by blocking the antigen-mediated calcium ion influx into mast cells. This prevents mast cell degranulation, resulting in mast cell stabilization and inhibition of the release of inflammatory mediators, histamine and leukotrienes, which are involved in the allergic process. Pemirolast potassium also prevents inflammatory mediator release from eosinophils. |
l Storage |
Storage temp. | -20°C |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
