l General Information |
Product Name | Pergolide Mesylate |
General description | Pergolide Mesylate is an antiparkinsonian agent which functions as a dopaminergic agonist. |
Synonym | LY127809 |
Purity | ≥98.0%(HPLC) | CAS Number | 66104-23-2 |
Formula | C20H30N2O3S2 | Molecular Weight | 410.591 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | White or off-white Solid |
Solubility(25°C) | DMSO | ≥5mg/mL |
Water | ≥50mg/mL |
l Biological Information |
Biochem/Physiol
Actions | Pergolide Mesylate is a semi-synthetic ergot derivative and a dopamine agonist with antiparkinson property. Pergolide mesylate binds to and activates dopamine receptor subtypes D1 and D2, resulting in prolactin secretion inhibition, transient increase in serum concentration of growth hormone, and decrease in serum concentration of luteinizing hormone. Direct stimulation of postsynaptic dopamine receptors in the nigrostriatal system, may account for this agent's antiparkinson activity. |
l Storage |
Storage temp. | -20°C |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
