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Lycorine

Product #: TS1596
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l  General Information

Product Name

Lycorine

General description

Lycorine is a toxic crystalline alkaloid found in various Amaryllidaceae species that weakly inhibits acetylcholinesterase (AChE) and ascorbic acid biosynthesis.

Synonym

Galanthidine, Amarylline, Narcissine, Licorine, Belamarine

Purity

≥98.0%(HPLC)

CAS Number

476-28-8

Formula

C16H17NO4

Molecular Weight

287.315

Suitability

BioReagent, suitable for cell culture, etc.

l  Physical and Chemical Information

Appearance

Solid

Solubility(25°C)

DMSO

≥45mg/mL

l  Biological Information

Biochem/Physiol  Actions

Lycorine is an indolizidine alkaloid that is 3,12-didehydrogalanthan substituted by hydroxy groups at positions and 2 and a methylenedioxy group across positions 9 and 10. Isolated from Crinum asiaticum, it has been shown to exhibit antimalarial activity. It has a role as a protein synthesis inhibitor, an antimalarial and a plant metabolite. It derives from a hydride of a galanthan.

l  Storage

Storage temp.

-20°C

l  Precautions and Disclaimer

This product is for R&D use only, not for drug, household, or other uses.

l  References

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov

 

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