l General Information |
Product Name | Harmine |
General description | Harmine is an alkaloid of the β-carboline family that regulates PPARγ through inhibition of the Wnt signaling pathway. It also selectively binds to MAO-A and reversibly inhibits monoamine oxidase A (MAO-A) but not the variant MAO-B. |
Synonym | telepathine; 7-methoxy-1-methyl-9H-pyrido[3,4-b]indole |
Purity | ≥98.0%(HPLC) | CAS Number | 442-51-3 |
Formula | C13H12N2O | Molecular Weight | 212.252 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | White or Off-white Solid |
Solubility(25°C) | DMSO | ≥35mg/mL |
l Biological Information |
Biochem/Physiol
Actions | Harmine is a harmala alkaloid in which the harman skeleton is methoxy-substituted at C-7. It has a role as a metabolite, an anti-HIV agent and an EC 1.4.3.4 (monoamine oxidase) inhibitor. It derives from a hydride of a harman. |
l Storage |
Storage temp. | -20°C |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
