l General Information |
Product Name | Harmine hydrochloride |
General description | Harmine hydrochloride, a fluorescent harmala alkaloid belonging to the beta-carboline family of compounds, is a highly cell-permeant and competitive inhibitor of ATP binding to the kinase pocket of DYRK1A, with about 60-fold higher IC50 value for DYRK2. It can also inhibit monoamine oxidases (MAOs) and cdc-like kinases (CLKs). |
Synonym | telepathine hydrochloride; 7-methoxy-1-methyl-9H-pyrido[3,4-b]indole;hydrochloride |
Purity | ≥98.0%(HPLC) | CAS Number | 343-27-1 |
Formula | C13H13ClN2O | Molecular Weight | 248.71 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | Faint Yellow to Yellow Solid |
Solubility(25°C) | DMSO | ≥15mg/mL |
Water | ≥15mg/mL |
l Storage |
Storage temp. | -20°C |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |