l General Information |
Product Name | N-Ethylmaleimide |
General description | N-Ethylmaleimide is an organic compound that is derived from maleic acid. It is an irreversible inhibitor of all cysteine peptidases, with alkylation occurring at the active site thiol group. |
Synonym | 1-ethylpyrrole-2,5-dione; NEM |
Purity | ≥98.0%(HPLC) | CAS Number | 128-53-0 |
Formula | C6H7NO2 | Molecular Weight | 125.127 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | White to off-white Solid |
Solubility(25°C) | DMSO | ≥15mg/mL |
Ethanol | ≥15mg/mL |
Water | ≥15mg/mL |
l Biological Information |
Biochem/Physiol
Actions | N-ethylmaleimide is a member of the class of maleimides that is the N-ethyl derivative of maleimide. It has a role as an EC 2.1.1.122 [(S)-tetrahydroprotoberberine N-methyltransferase] inhibitor, an EC 2.7.1.1 (hexokinase) inhibitor and an EC 1.3.1.8 [acyl-CoA dehydrogenase (NADP(+))] inhibitor. It derives from a maleimide. |
l Storage |
Storage temp. | -20°C |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
