Product Name

Demethylzeylasteral

General description

Demethylzeylasteral, the active component isolated from Tripterygium wilfordii Hook F., inhibits UDP-glucuronosyltransferase (UGT) isoforms UGT1A6 and UGT2B7 with immunosuppressive effects.

Synonym

T-96

Purity

≥99.0%(HPLC)

CAS Number

107316-88-1

Formula

C²⁹H³⁶O⁶

Molecular Weight

480.601

Suitability

BioReagent, suitable for cell culture, etc.

l  Physical and Chemical Information

Appearance

Solid

Solubility(25°C)

DMSO

≥50mg/mL

Ethanol

≥25mg/mL

Water

Insoluble

l  Biological Information

Biochem/Physiol  Actions

Demethylzeylasteral has a role as a plant metabolite, an EC 2.4.1.17(glucuronosyltransferase) inhibitor, an immunosuppressive agent, an anti-inflammatory agent and a nephroprotective agent.

l  Storage

Storage temp.

-20°C

l  Precautions and Disclaimer

This product is for R&D use only, not for drug, household, or other uses.

l  References

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov