Phone:| Tech Support:| E-mail:
Home > Products > Small molecule > Neuronal Signaling > Fexofenadine HCl

Fexofenadine HCl

Product #: TS1315
Image SKU-Pack Size Stock Price($) Quantity

Documents

Details

l  General Information

Product Name

Fexofenadine HCl

General description

Fexofenadine HCl inhibits histamine H1 receptor with IC50 of 246 nM.

Synonym

MDL 16455A; 2-[4-[1-hydroxy-4-[4-[hydroxy(diphenyl)methyl]piperidin-1-yl]butyl]phenyl]-2-methylpropanoic acid; hydrochloride

Purity

≥98.0%(HPLC)

CAS Number

153439-40-8

Formula

C32H40ClNO4

Molecular Weight

538.125

Suitability

BioReagent, suitable for cell culture, etc.

l  Physical and Chemical Information

Appearance

White to beige Solid

Solubility(25°C)

DMSO

≥50mg/mL

Ethanol

≥50mg/mL

Water

Slightly soluble

l  Biological Information

Biochem/Physiol  Actions

Fexofenadine Hydrochloride is the hydrochloride salt form of fexofenadine, a carboxylated metabolic derivative of terfenadine and second generation, long-lasting selective histamine H1 receptor antagonist, with antihistaminic activity. Upon administration, fexofenadine competitively binds of peripheral H1-receptors in the gastrointestinal (GI) tract, blood vessels, and bronchial smooth muscle. This prevents binding of histamine to peripheral H1-receptors and prevents their activation. This prevents a histamine-mediated allergic reaction. Fexofenadine does not cross the blood-brain-barrier (BBB).

l  Storage

Storage temp.

-20°C

l  Precautions and Disclaimer

This product is for R&D use only, not for drug, household, or other uses.

l  References

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov

 

天问科技