l General Information |
Product Name | Ibandronate sodium |
General description | Ibandronate sodium is a highly potent nitrogen-containing bisphosphonate used for the treatment of osteoporosis. |
Synonym | BM-21.0955; sodium; hydroxy-[1-hydroxy-3-[methyl(pentyl)amino]-1-phosphonopropyl]phosphinate;hydrate |
Purity | ≥98.0%(HPLC) | CAS Number | 138926-19-9 |
Formula | C9H25NNaO8P2 | Molecular Weight | 359.227 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | Solid |
Solubility(25°C) | DMSO | Insolube |
Ethanol | Insolube |
Water | ≥50mg/mL |
l Biological Information |
Biochem/Physiol
Actions | Ibandronate Sodium is the sodium salt form of ibandronic acid, a synthetic nitrogen-containing bisphosphonate. Ibandronic acid inhibits farnesyl pyrophosphate synthase, resulting in a reduction in geranylgeranyl GTPase signaling proteins and apoptosis of osteoclasts. This agent increases bone mineral density, decreases bone remodeling, inhibits osteoclast-mediated bone resorption, and reduces metastases-related and corticosteroid-related bone pain. |
l Storage |
Storage temp. | -20°C |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
