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Home > Products > Small molecule > Metabolism > Evacetrapib (LY2484595)

Evacetrapib (LY2484595)

Product #: TS1222
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Details

l  General Information

Product Name

Evacetrapib

General description

Evacetrapib is a potent and selective inhibitor of CETP with IC50 of 5.5 nM, elevates HDL cholesterol without increases in aldosterone or blood pressure.

Synonym

LY2484595

Purity

≥98.0%(HPLC)

CAS Number

1186486-62-3

Formula

C31H36F6N6O2

Molecular Weight

638.659

Suitability

BioReagent, suitable for cell culture, etc.

l  Physical and Chemical Information

Appearance

Solid

Solubility(25°C)

DMSO

≥5mg/mL

Ethanol

≥5mg/mL

Water

Insoluble

l  Biological Information

Biochem/Physiol  Actions

Evacetrapib has been used in trials studying the basic science and treatment of Dyslipidemia, Hyperlipidemia, Hypercholesterolemia, Hepatic Insufficiency, and Cardiovascular Disease.

l  Storage

Storage temp.

-20°C

l  Precautions and Disclaimer

This product is for R&D use only, not for drug, household, or other uses.

l  References

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov

 

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