l General Information |
Product Name | (-)-MK 801 maleate |
General description | (-)-MK-801 maleate is a potent N-methyl-D-aspartate (NMDA) receptor antagonist with Ki of 30.5 nM. |
Synonym | Dizocilpine maleate; C13737 maleate |
Purity | ≥98.0%(HPLC) | CAS Number | 121917-57-5 |
Formula | C20H19NO4 | Molecular Weight | 337.375 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | Solid |
Solubility(25°C) | DMSO | ≥50mg/mL |
Ethanol | ~5mg/mL |
Water | Insoluble |
l Biological Information |
Biochem/Physiol
Actions | A potent noncompetitive antagonist of the NMDA receptor (RECEPTORS, N-METHYL-D-ASPARTATE) used mainly as a research tool. The drug has been considered for the wide variety of neurodegenerative conditions or disorders in which NMDA receptors may play an important role. Its use has been primarily limited to animal and tissue experiments because of its psychotropic effects. |
l Storage |
Storage temp. | -20°C |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
