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TPCA-1

Product #: TS1173
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Details

l  General Information

Product Name

TPCA-1

General description

TPCA-1 is an inhibitor of IKK-2 with IC50 of 17.9 nM in a cell-free assay, inhibits NF-κB pathway, exhibits 22-fold selectivity over IKK-1.

Synonym

GW683965; 2-(carbamoylamino)-5-(4-fluorophenyl)thiophene-3-carboxamide

Purity

≥98.0%(HPLC)

CAS Number

507475-17-4

Formula

C12H10FN3O2S

Molecular Weight

279.289

Suitability

BioReagent, suitable for cell culture, etc.

l  Physical and Chemical Information

Appearance

White to Light brown Solid

Solubility(25°C)

DMSO

≥45mg/mL

Ethanol

Insoluble

Water

Insoluble

l  Storage

Storage temp.

-20°C

l  Precautions and Disclaimer

This product is for R&D use only, not for drug, household, or other uses.

l  References

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov

 

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