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Home > Products > Small molecule > Angiogenesis > TAE226 (NVP-TAE226)

TAE226 (NVP-TAE226)

Product #: TS1171
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Details

l  General Information

Product Name

TAE226

General description

TAE226 is a potent FAK inhibitor with IC50 of 5.5 nM and modestly potent to Pyk2, ~10- to 100-fold less potent against  InsR, IGF-1R, ALK, and c-Met.

Synonym

NVP-TAE226; 2-[[5-chloro-2-(2-methoxy-4-morpholin-4-ylanilino)pyrimidin-4-yl]amino]-N-methylbenzamide

Purity

≥98.0%(HPLC)

CAS Number

761437-28-9

Formula

C23H25ClN6O3

Molecular Weight

468.942

Suitability

BioReagent, suitable for cell culture, etc.

l  Physical and Chemical Information

Appearance

Solid

Solubility(25°C)

DMSO

≥50mg/mL

Ethanol

Insoluble

Water

Insoluble

l  Storage

Storage temp.

-20°C

l  Precautions and Disclaimer

This product is for R&D use only, not for drug, household, or other uses.

l  References

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov

 

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