l General Information |
Product Name | M344 |
General description | M344 is a potent HDAC inhibitor with IC50 of 100 nM and able to induce cell differentiation. |
Synonym | 4-(dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamide |
Purity | ≥98.0%(HPLC) | CAS Number | 251456-60-7 |
Formula | C16H25N3O3 | Molecular Weight | 307.394 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | White to beige Solid |
Solubility(25°C) | DMSO | ≥50mg/mL |
Ethanol | Slightly soluble |
Water | Insoluble |
l Biological Information |
Biochem/Physiol
Actions | A hydroxamic acid and anilide derivative that acts as a HISTONE DEACETYLASE inhibitor. It is used in the treatment of CUTANEOUS T-CELL LYMPHOMA and SEZARY SYNDROME. |
l Storage |
Storage temp. | -20°C |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
