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AZ 3146

Product #: TS1130
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Details

l  General Information

Product Name

AZ 3146

General description

AZ3146 is a selective Mps1 inhibitor with IC50 of ~35 nM, contributes to recruitment of CENP-E (kinesin-related motor protein), less potent to FAK, JNK1, JNK2, and Kit.

Synonym

9-cyclopentyl-2-[2-methoxy-4-(1-methylpiperidin-4-yl)oxyanilino]-7-methylpurin-8-one

Purity

≥98.0%(HPLC)

CAS Number

1124329-14-1

Formula

C24H32N6O3

Molecular Weight

452.559

Suitability

BioReagent, suitable for cell culture, etc.

l  Physical and Chemical Information

Appearance

White to Light brown Solid

Solubility(25°C)

DMSO

≥25mg/mL

Ethanol

≥50mg/mL

Water

Insoluble

l  Storage

Storage temp.

-20°C

l  Precautions and Disclaimer

This product is for R&D use only, not for drug, household, or other uses.

l  References

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov

 

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