l General Information |
Product Name | Nilvadipine |
General description | Nilvadipine is a potent calcium channel blocker with an IC50 of 0.03 nM. |
Synonym | ARC029; FR34235; 3-O-methyl 5-O-propan-2-yl 2-cyano-6-methyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate |
Purity | ≥98.0%(HPLC) | CAS Number | 75530-68-6 |
Formula | C19H19N3O6 | Molecular Weight | 385.376 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | White to beige Solid |
Solubility(25°C) | DMSO | ≥50mg/mL |
Ethanol | ≥25mg/mL |
Water | Insoluble |
l Biological Information |
Biochem/Physiol
Actions | Nilvadipine is similar to other dihydropyridines including amlodipine, felodipine, isradipine, and nicardipine. Nilvadipine is used to treat Prinzmetal's angina, hypertension, and other vascular disorders such as Raynaud's phenomenon. By blocking the calcium channels, Nifedipine inhibits the spasm of the coronary artery and dilates the systemic arteries, results in a increase of myocardial oxygen supply and a decrease in systemic blood pressure. |
l Storage |
Storage temp. | -20°C |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
