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Home > Products > Small molecule > Metabolism > Nepicastat (SYN-117) HCl

Nepicastat (SYN-117) HCl

Product #: TS1119
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Details

l  General Information

Product Name

Nepicastat HCl

General description

Nepicastat HCl is a potent and selective inhibitor of both bovine and human dopamine-β-hydroxylase with IC50 of 8.5 nM and 9 nM, with negligible affinity for twelve other enzymes and thirteen neurotransmitter receptors.

Synonym

SYN-117 HCl; 4-(aminomethyl)-3-[(2S)-5,7-difluoro-1,2,3,4-tetrahydronaphthalen-2-yl]-1H-imidazole-2-thione; hydrochloride

Purity

≥98.0%(HPLC)

CAS Number

170151-24-3

Formula

C14H16ClF2N3S

Molecular Weight

331.81

Suitability

BioReagent, suitable for cell culture, etc.

l  Physical and Chemical Information

Appearance

White to beige Solid

Solubility(25°C)

DMSO

≥50mg/mL

Ethanol

Insoluble

Water

Insoluble

l  Storage

Storage temp.

-20°C

l  Precautions and Disclaimer

This product is for R&D use only, not for drug, household, or other uses.

l  References

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov

 

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