Product Name

Tiotropium Bromide hydrate

General description

Tiotropium Bromide hydrate is a monohydrate of tiotropium bromide (Spiriva Tiova BA 679BR tiopropium) that is an  anticholinergic and bronchodilator and a muscarinic receptor antagonist.

Synonym

BA 679BR

Purity

≥98.0%(HPLC)

CAS Number

139404-48-1

Formula

C¹⁹H²⁴BrNO⁵S²

Molecular Weight

490.427

Suitability

BioReagent, suitable for cell culture, etc.

l  Physical and Chemical Information

Appearance

Solid

Solubility(25°C)

DMSO

≥50mg/mL

Ethanol

Insoluble

Water

Insoluble

l  Biological Information

Biochem/Physiol  Actions

Tiotropium Bromide Monohydrate is the monohydrate bromide salt form of tiotropium, a quaternary ammonium derivative of atropine and a long-acting muscarinic receptor antagonist, with bronchodilating activity. Upon inhalation, tiotropium binds to and blocks mainly muscarinic M3 receptors located on smooth muscle cells, thereby preventing smooth muscle contraction.

l  Storage

Storage temp.

-20°C

l  Precautions and Disclaimer

This product is for R&D use only, not for drug, household, or other uses.

l  References

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov