l General Information |
Product Name | Ciclopirox |
General description | Ciclopirox is a broad-spectrum antifungal agent working as an iron chelator. |
Synonym | 6-cyclohexyl-1-hydroxy-4-methylpyridin-2-one |
Purity | ≥98.0%(HPLC) | CAS Number | 29342-05-0 |
Formula | C12H17NO2 | Molecular Weight | 207.273 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | Solid |
Solubility(25°C) | DMSO | ≥35mg/mL |
Ethanol | ≥35mg/mL |
Water | Insoluble |
l Biological Information |
Biochem/Physiol
Actions | Ciclopirox is a synthetic, broad-spectrum antifungal agent with additional antibacterial and anti-inflammatory activities. Ciclopirox exerts its action by binding to and chelating trivalent cations, such as Fe3+ and Al3+, thereby inhibiting the availability of essential co-factors for enzymes. This may lead to a loss of activity of enzymes that are essential for cellular metabolism, organization of cell wall structure and other crucial cell functions. In addition, ciclopirox exerts its anti-inflammatory activity by inhibiting 5-lipoxygenase and cyclooxygenase (COX). |
l Storage |
Storage temp. | -20°C |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
