l General Information |
Product Name | Mycophenolic acid |
General description | Mycophenolic acid is a potent IMPDH inhibitor and the active metabolite of an immunosuppressive drug, used to prevent rejection in organ transplantation. |
Synonym | Mycophenolate; RS-61443 |
Purity | ≥98.0%(HPLC) | CAS Number | 24280-93-1 |
Formula | C17H20O6 | Molecular Weight | 320.341 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | White to White w/ Yellow solid |
Solubility(25°C) | DMSO | ≥50mg/mL |
Ethanol | ~5mg/mL |
Water | Insoluble |
l Biological Information |
Biochem/Physiol
Actions | Mycophenolic Acid is an antineoplastic antibiotic derived from various Penicillium fungal species. Mycophenolic acid is an active metabolite of the prodrug mycophenolate mofetil. Mycophenolic acid inhibits inosine monophosphate dehydrogenase (IMPDH), preventing the formation of guanosine monophosphate and synthesis of lymphocyte DNA that results in inhibition of lymphocyte proliferation, antibody production, cellular adhesion, and migration of T and B lymphocytes. Mycophenolic acid also has antibacterial, antifungal, and antiviral activities. |
l Storage |
Storage temp. | -20°C |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
