Product Name

Gambogic Acid

General description

Gambogic Acid activates caspases with EC50 of 0.78-1.64 &muM and competitively inhibits Bcl-XL, Bcl-2, Bcl-W, Bcl-B, Bfl-1 and Mcl-1 with IC50 of 1.47, 1.21, 2.02, 0.66, 1.06 and 0.79 &muM, respectively.

Synonym

Guttatic Acid; Guttic Acid

Purity

≥98.0%(HPLC)

CAS Number

2752-65-0

Formula

C³⁸H⁴⁴O⁸

Molecular Weight

628.762

Suitability

BioReagent, suitable for cell culture, etc.

l  Physical and Chemical Information

Appearance

Yellow to Orange Solid

Solubility(25°C)

DMSO

≥50mg/mL

Ethanol

≥50mg/mL

Water

Insoluble

l  Storage

Storage temp.

-20°C

l  Precautions and Disclaimer

This product is for R&D use only, not for drug, household, or other uses.

l  References

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov