l General Information |
Product Name | Tolbutamide |
General description | Tolbutamide is an inhibitor of potassium channel, used for type II diabetes. |
Synonym | HLS 831; 1-butyl-3-(4-methylphenyl)sulfonylurea |
Purity | ≥98.0%(HPLC) | CAS Number | 64-77-7 |
Formula | C12H18N2O3S | Molecular Weight | 270.347 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | White to Off White Solid |
Solubility(25°C) | DMSO | ≥45mg/mL |
Ethanol | ≥45mg/mL |
Water | Insoluble |
l Biological Information |
Biochem/Physiol
Actions | Tolbutamide is a short-acting, first-generation sulfonylurea with hypoglycemic activity. Compared to second-generation sulfonylureas, tolbutamide is more likely to cause adverse effects, such as jaundice. This agent is rapidly metabolized by CYPC29. |
l Storage |
Storage temp. | -20°C |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
