l General Information |
Product Name | NVP-BHG712 |
General description | NVP-BHG712 is a specific EphB4 inhibitor with ED50 of 25 nM that discriminates between VEGFR and EphB4 inhibition also shows activity against c-Raf, c-Src and c-Abl with IC50 of 0.395 μM,1.266 μM and 1.667 μM, respectively. |
Synonym | 4-methyl-3-[(1-methyl-6-pyridin-3-ylpyrazolo[3,4-d]pyrimidin-4-yl)amino]-N-[3-(trifluoromethyl)phenyl]benzamide |
Purity | ≥98.0%(HPLC) | CAS Number | 940310-85-0 |
Formula | C26H20F3N7O | Molecular Weight | 503.489 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | White to Beige Powder |
Solubility(25°C) | DMSO | ≥50mg/mL |
Ethanol | Slightly soluble |
Water | Insoluble |
l Storage |
Storage temp. | -20°C |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
