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Elvitegravir (GS-9137, JTK-303)

Product #: TS0806
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l  General Information

Product Name

Elvitegravir

General description

Elvitegravir is an HIV integrase inhibitor for HIV-1 IIIB, HIV-2 EHO and HIV-2 ROD with IC50 of 0.7 nM, 2.8 nM and 1.4 nM in cell-free assays, respectively.

Synonym

GS-9137, JTK-303

Purity

≥98.0%(HPLC)

CAS Number

697761-98-1

Formula

C23H23ClFNO5

Molecular Weight

447.887

Suitability

BioReagent, suitable for cell culture, etc.

l  Physical and Chemical Information

Appearance

Solid

Solubility(25°C)

DMSO

≥50mg/mL

Ethanol

≥25mg/mL

Water

Insoluble

l  Biological Information

Biochem/Physiol  Actions

Elvitegravir is a modified quinolone antibiotic with activity against human immunodeficiency virus 1. Elvitegravir is an inhibitor of viral integrase and retains activity against integrase mutants that are resistant to Raltegravir.

l  Storage

Storage temp.

-20°C

l  Precautions and Disclaimer

This product is for R&D use only, not for drug, household, or other uses.

l  References

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov

 

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