l General Information |
Product Name | Rimantadine |
General description | Rimantadine is an anti-influenza virus drug for T. brucei with IC50 of 7 μM. |
Synonym | 1-(1-adamantyl)ethanamine; Flumadine |
Purity | ≥98.0%(HPLC) | CAS Number | 13392-28-4 |
Formula | C12H21N | Molecular Weight | 179.307 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | Solid |
Solubility(25°C) | DMSO | ≥15mg/mL |
Ethanol | ≥15mg/mL |
Water | ≥15mg/mL |
l Biological Information |
Biochem/Physiol
Actions | Rimantadine is a cyclic amine and alpha-methyl derivative of amantadine with antiviral activity. Although the exact mechanism of action of rimantadine is not understood, this agent appears to exert its antiviral effect against influenza A virus by interfering with the function of the transmembrane domain of the viral M2 protein, thereby preventing the uncoating of the virus and subsequent release of infectious viral nucleic acids into the cytoplasm of infected cells. |
l Storage |
Storage temp. | -20°C |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
