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Sulfamethoxazole

Product #: TS0774
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Details

l  General Information

Product Name

Sulfamethoxazole

General description

Sulfamethoxazole is a sulfonamide bacteriostatic antibiotic with an IC50 of 2.7 μM.

Synonym

4-amino-N-(5-methyl-1,2-oxazol-3-yl)benzenesulfonamide

Purity

≥98.0%(HPLC)

CAS Number

723-46-6

Formula

C10H11N3O3S

Molecular Weight

253.276

Suitability

BioReagent, suitable for cell culture, etc.

l  Physical and Chemical Information

Appearance

White or almost White Solid

Solubility(25°C)

DMSO

≥35mg/mL

Ethanol

≥5mg/mL

Water

Very slightly soluble

l  Biological Information

Biochem/Physiol  Actions

Sulfamethoxazole is a sulfonamide bacteriostatic antibiotic that is most commonly used in combination with trimethoprim as the drug Bactrim. Sulfamethoxazole competitively inhibits dihydropteroate synthase preventing the formation of dihydropteroic acid, a precursor of folic acid which is required for bacterial growth.

Application

Anti-Infective Agents

l  Storage

Storage temp.

-20°C

l  Precautions and Disclaimer

This product is for R&D use only, not for drug, household, or other uses.

l  References

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov

 

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