Phone:| Tech Support:| E-mail:
Home > Products > Small molecule > Neuronal Signaling > Diclofenac Sodium

Diclofenac Sodium

Product #: TS0768
Image SKU-Pack Size Stock Price($) Quantity

Documents

Details

l  General Information

Product Name

Diclofenac Sodium

General description

Diclofenac Sodium is a non-selective COX inhibitor with IC50 of 0.5 μg/ml and 0.5 μg/ml for COX-1 and -2 in intact cells, respectively, used as a nonsteroidal anti-inflammatory drug (NSAID) to relieve pain and reduce swelling in flammation.

Synonym

GP 45840; sodium; 2-[2-(2,6-dichloroanilino)phenyl]acetate

Purity

≥98.0%(HPLC)

CAS Number

15307-79-6

Formula

C14H10Cl2NNaO2

Molecular Weight

318.129

Suitability

BioReagent, suitable for cell culture, etc.

l  Physical and Chemical Information

Appearance

White or Slightly Yellow Solid

Solubility(25°C)

DMSO

≥45mg/mL

Ethanol

≥45mg/mL

Water

~5mg/mL

l  Biological Information

Biochem/Physiol  Actions

Diclofenac Sodium is the sodium salt form of diclofenac, a benzene acetic acid derivate and nonsteroidal anti-inflammatory drug (NSAID) with analgesic, antipyretic and anti-inflammatory activity. Diclofenac sodium is a non-selective reversible and competitive inhibitor of cyclooxygenase (COX), subsequently blocking the conversion of arachidonic acid into prostaglandin precursors. This leads to an inhibition of the formation of prostaglandins that are involved in pain, inflammation and fever.

l  Storage

Storage temp.

-20°C

l  Precautions and Disclaimer

This product is for R&D use only, not for drug, household, or other uses.

l  References

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov

 

天问科技