l General Information |
Product Name | Etidronic acid( |
General description | Etidronic acid( is a non-aminobisphosphonate, show protein tyrosine phosphatase (PTP) inhibitory activity, used for the treatment of Paget's disease and the prevention of heterotopic ossification. |
Synonym | (1-hydroxy-1-phosphonoethyl)phosphonic acid |
Assay | 60% aqueous solution; 55.0 - 65.0%(Titroation by NaOH) | CAS Number | 2809-21-4 |
Formula | C2H8O7P2 | Molecular Weight | 206.027 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | Colorless to Faint Yellow Liquid |
Solubility(25°C) | DMSO | Insoluble |
Ethanol | Insoluble |
Water | ≥25mg/mL |
l Biological Information |
Biochem/Physiol
Actions | As a member of the family of drugs known as bisphosphonates, etidronate differs from endogenous pyrophosphate in its resistance to enzymatic hydrolysis. This agent adsorbs to hydroxyapatite cells and reduces the number of osteoclasts, thereby inhibiting abnormal bone resorption. Etidronate may also directly stimulate bone formation by osteoblasts. |
l Storage |
Storage temp. | -20°C |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
