l General Information |
Product Name | Penicillamine |
General description | Penicillamine is used as an antirheumatic and as a chelating agent in Wilson’s disease. |
Synonym | Dimethyl Cysteine; (2S)-2-amino-3-methyl-3-sulfanylbutanoic acid |
Purity | ≥98.0%(HPLC) | CAS Number | 52-67-5 |
Formula | C5H11NO2S | Molecular Weight | 149.208 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | White or off-white Solid |
Solubility(25°C) | DMSO | Very slightly soluble |
Ethanol | Insoluble |
Water | ≥15mg/mL |
l Biological Information |
Biochem/Physiol
Actions | Penicillamine is a beta dimethyl analog of the amino acid cysteine. As a degradation product of penicillin antibiotics, penicillamine chelates with heavy metals and increases their urinary excretion. Possessing antineoplastic properties, penicillamine induces apoptosis by a p53-mediated mechanism and inhibits angiogenesis by chelating with copper, a cofactor for angiogenesis. |
l Storage |
Storage temp. | -20°C |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
