l General Information |
Product Name | Lomustine |
General description | Lomustine inhibits cancer cells by damaging the DNA and stops cells from dividing. |
Synonym | NSC79037; 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea |
Purity | ≥98.0%(HPLC) | CAS Number | 13010-47-4 |
Formula | C9H16ClN3O2 | Molecular Weight | 233.696 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | Solid |
Solubility(25°C) | DMSO | ≥25mg/mL |
Ethanol | ≥25mg/mL |
Water | Very slightly soluble |
l Biological Information |
Biochem/Physiol
Actions | Lomustine is a nitrosourea with antineoplastic activity. Lomustine alkylates and crosss DNA, thereby inhibiting DNA and RNA synthesis. This agent also carbamoylates DNA and proteins, resulting in inhibition of DNA and RNA synthesis and disruption of RNA processing. Lomustine is lipophilic and crosses the blood-brain barrier. |
l Storage |
Storage temp. | -20°C |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
