l General Information |
Product Name | Betaxolol HCl |
General description | Betaxolol is a β1 adrenergic receptor blocker with IC50 of 6 μM. |
Synonym | SL 75212 HCl; 1-[4-[2-(cyclopropylmethoxy)ethyl]phenoxy]-3-(propan-2-ylamino)propan-2-ol; hydrochloride |
Purity | ≥98.0%(HPLC) | CAS Number | 63659-19-8 |
Formula | C18H30ClNO3 | Molecular Weight | 343.892 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | Solid |
Solubility(25°C) | DMSO | ≥45mg/mL |
Ethanol | ≥45mg/mL |
Water | ≥50mg/mL |
l Biological Information |
Biochem/Physiol
Actions | Betaxolol Hydrochloride is the hydrochloride salt form of betaxolol, a beta-1-selective adrenergic receptor antagonist without intrinsic sympathomimetic activity. Betaxolol hydrochloride acts on the heart and circulatory system and decreases cardiac contractility and rate, thereby reducing cardiac output. When applied topically in the eye, it lowers intraocular pressure by reducing aqueous humor secretion. |
l Storage |
Storage temp. | -20°C |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
