l General Information |
Product Name | Ethionamide |
General description | Ethionamide is an antibiotic used in the treatment of tuberculosis. |
Synonym | Bayer 5312; 2-ethylpyridine-4-carbothioamide |
Purity | ≥98.0%(HPLC) | CAS Number | 536-33-4 |
Formula | C8H10N2S | Molecular Weight | 166.242 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | Light Yellow to Yellow Solid |
Solubility(25°C) | DMSO | ≥15mg/mL |
Ethanol | ~5mg/mL |
Water | Very slightly soluble |
l Biological Information |
Biochem/Physiol
Actions | Ethionamide is a nicotinamide derivative, with antibacterial activity, used to treat tuberculosis. Although the exact mechanism of action of ethionamide is unknown, it may inhibit the synthesis of mycolic acid, a saturated fatty acid found in the bacterial cell wall, thereby inhibiting bacterial cell wall synthesis. This eventually leads to bacterial cell wall disruption and cell lysis. Ethionamide may be bacteriostatic or bactericidal in action, depending on the concentration of the drug at the site of infection and the susceptibility of the organism involved. |
l Storage |
Storage temp. | -20°C |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
