Product Name

Chlorprothixene

General description

Chlorprothixene has strong binding affinities to dopamine and histamine receptors, such as  D1, D2, D3, D5, H1, 5-HT2, 5-HT6 and 5-HT7, with Ki of 18 nM, 2.96 nM, 4.56 nM, 9 nM, 3.75 nM, 9.4 nM, 3 nM and 5.6 nM, respectively.

Synonym

(3Z)-3-(2-chlorothioxanthen-9-ylidene)-N,N-dimethylpropan-1-amine

Purity

≥98.0%(HPLC)

CAS Number

113-59-7

Formula

C¹⁸H¹⁸ClNS

Molecular Weight

315.859

Suitability

BioReagent, suitable for cell culture, etc.

l  Physical and Chemical Information

Appearance

Solid

Solubility(25°C)

DMSO

Slightly soluble

Ethanol

≥5mg/mL

Water

Very slightly soluble

l  Biological Information

Biochem/Physiol  Actions

A thioxanthine with effects similar to the phenothiazine antipsychotics.

l  Storage

Storage temp.

-20°C

l  Precautions and Disclaimer

This product is for R&D use only, not for drug, household, or other uses.

l  References

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov