l General Information |
Product Name | Pyrazinamide |
General description | Pyrazinamide is an agent used to treat tuberculosis. |
Synonym | Pyrazinoic Acid Amide; pyrazine-2-carboxamide |
Purity | ≥98.0%(HPLC) | CAS Number | 98-96-4 |
Formula | C5H5N3O | Molecular Weight | 123.115 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | White or off-white Solid |
Solubility(25°C) | DMSO | ≥5mg/mL |
Ethanol | Very slightly soluble |
Water | ~5mg/mL |
l Biological Information |
Biochem/Physiol
Actions | Pyrazinamide is a synthetic pyrazinoic acid amide derivative with bactericidal property. Pyrazinamide is particularly active against slowly multiplying intracellular bacilli (unaffected by other drugs) by an unknown mechanism of action. Its bactericidal action is dependent upon the presence of bacterial pyrazinamidase, which removes the amide group to produce active pyrazinoic acid. Pyrazinamide is an important component of multidrug therapy for tuberculosis. |
l Storage |
Storage temp. | -20°C |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
