l General Information |
Product Name | Mesna |
General description | Mesna, a sulfhydryl compound that is used to reduce the incidence of hemorrhagic cystitis associated with certain chemotherapeutic agents. |
Synonym | sodium;2-sulfanylethanesulfonate |
Purity | ≥98.0%(HPLC) | CAS Number | 19767-45-4 |
Formula | C2H5NaO3S2 | Molecular Weight | 164.169 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | White to Yellow Solid |
Solubility(25°C) | DMSO | ≥15mg/mL |
Ethanol | Insoluble |
Water | Slightly soluble |
l Biological Information |
Biochem/Physiol
Actions | Mesna is a sulfhydryl compound that is used to reduce the incidence of hemorrhagic cystitis associated with certain chemotherapeutic agents. Mesna is converted to a free thiol compound in the kidney, where it binds to and inactivates acrolein and other urotoxic metabolites of ifosfamide and cyclophosphamide, thereby reducing their toxic effects on the urinary tract during urinary excretion. |
l Storage |
Storage temp. | -20°C |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
