l General Information |
Product Name | Mesalamine |
General description | Mesalamine is a specific inhibitor of TNFα-induced IKK activity, used to treat inflammatory bowel disease. |
Synonym | 5-Aminosalicylic acid; 5-amino-2-hydroxybenzoic acid |
Purity | ≥98.0%(HPLC) | CAS Number | 89-57-6 |
Formula | C7H7NO3 | Molecular Weight | 153.137 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | White to pale brown solid |
Solubility(25°C) | DMSO | ≥15mg/ml |
Ethanol | ≥15mg/ml |
Water | Very slightly soluble |
l Biological Information |
Biochem/Physiol
Actions | Mesalamine is an agent derived from sulfasalazine, an antiinflammatory agent. Mesalamine may reduce inflammation through inhibition of cyclooxygenase and prostaglandin production. Following rectal or oral administration, only a small amount of mesalamine is absorbed; the remainder, acting topically, reduces bowel inflammation, diarrhea, rectal bleeding and stomach pain. |
l Storage |
Storage temp. | -20°C |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
