l General Information |
Product Name | Monobenzone |
General description | Monobenzone is a compound used as a topical agent for medical depigmentation. It can specifically block tyrosinase. |
Synonym | 4-phenylmethoxyphenol |
Purity | ≥98.0%(HPLC) | CAS Number | 103-16-2 |
Formula | C13H12O2 | Molecular Weight | 200.237 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | White or off-white to pale brown solid |
Solubility(25°C) | DMSO | ≥25mg/ml |
Ethanol | ≥25mg/ml |
Water | Very slightly soluble |
l Biological Information |
Biochem/Physiol
Actions | Monobenzone is a monobenzyl ether of hydroquinone with topical depigmentation activity. Although the exact mechanism of action of depigmentation is unknown, the metabolites of monobenzone appear to have a cytotoxic effect on melanocytes. Furthermore, the depigmentation effect might be mediated through the inhibition of tyrosinase, which is essential in the synthesis of melanin pigments, thereby causing permanent depigmentation of the skin. |
l Storage |
Storage temp. | -20°C |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
