l General Information |
Product Name | Methimazole |
General description | Methimazole is an antithyroid medicine. |
Synonym | Tapazole; Thiamazole; 3-methyl-1H-imidazole-2-thione |
Purity | ≥98.0%(HPLC) | CAS Number | 60-56-0 |
Formula | C4H6N2S | Molecular Weight | 114.166 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | White or off-white solid |
Solubility(25°C) | DMSO | ≥15mg/ml |
Ethanol | ≥15mg/ml |
Water | ≥15mg/ml |
l Biological Information |
Biochem/Physiol
Actions | Methimazole is a thioamide inhibitor of the enzyme thyroid peroxidase (TPO), with antithyroid activity. Upon administration, methimazole inhibits the metabolism of iodide and the iodination of tyrosine residues in the thyroid hormone precursor thyroglobulin by TPO; this prevents the synthesis of the thyroid hormones triiodothyronine (T3) and thyroxine (T4). |
l Storage |
Storage temp. | -20°C |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
