l  General Information  | 
Product Name  | PD318088  | 
General description  | PD318088 is a non-ATP competitive allosteric MEK1/2 inhibitor, binds simultaneously with ATP in a region of the MEK1 active site that is adjacent to the ATP-binding site.  | 
Synonym  | 5-bromo-N-(2,3-dihydroxypropoxy)-3,4-difluoro-2-(2-fluoro-4-iodoanilino)benzamide  | 
Purity  | ≥98.0%(HPLC)  | CAS Number  | 391210-00-7  | 
Formula  | C16H13BrF3IN2O4  | Molecular Weight  | 561.094  | 
Suitability  | BioReagent, suitable for cell culture, etc.  | 
l  Physical and Chemical Information  | 
Appearance  | Solid  | 
Solubility(25°C)  | DMSO  | ≥50mg/ml  | 
Ethanol  | ~5mg/ml  | 
Water  | Very slightly soluble  | 
l  Storage  | 
Storage temp.  | -20°C  | 
l  Precautions and Disclaimer  | 
This product is for R&D use only, not for drug, household, or other uses.  | 
l  References  | 
1.    http://www.drugbank.ca 2.    https://ncit.nci.nih.gov 3.    https://www.ncbi.nlm.nih.gov  |