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Dyphylline

Product #: TS0636
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l  General Information

Product Name

Dyphylline

General description

Dyphylline is a xanthine derivative with bronchodilator and vasodilator effects.

Synonym

Diprophylline; 7-(2,3-dihydroxypropyl)-1,3-dimethylpurine-2,6-dione

Purity

≥98.0%(HPLC)

CAS Number

479-18-5

Formula

C10H14N4O4

Molecular Weight

254.246

Suitability

BioReagent, suitable for cell culture, etc.

l  Physical and Chemical Information

Appearance

White or off-white Solid

Solubility(25°C)

DMSO

≥35mg/ml

Ethanol

Insoluble

Water

≥35mg/ml

l  Biological Information

Biochem/Physiol  Actions

Dyphylline is a xanthine derivative. Dyphilline exerts bronchodilator effects and to a lesser extent vasodilator and diuretic properties. Dyphilline probably acts as a competitive inhibitor of phosphodiesterase which leads to an increase in intracellular cAMP. This results in relaxation of bronchial smooth muscle and other smooth muscles. Dyphylline may also antagonize adenosine receptors. Dyphylline is used in the treatment of acute bronchial asthma, chronic bronchitis and emphysema.

l  Storage

Storage temp.

-20°C

l  Precautions and Disclaimer

This product is for R&D use only, not for drug, household, or other uses.

l  References

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov

 

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