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Betamethasone

Product #: TS0635
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Details

l  General Information

Product Name

Betamethasone

General description

Betamethasone is a glucocorticoid steroid with anti-inflammatory and immunosuppressive properties.

Synonym

NSC-39470; SCH-4831

Purity

≥98.0%(HPLC)

CAS Number

378-44-9

Formula

C22H29FO5

Molecular Weight

392.467

Suitability

BioReagent, suitable for cell culture, etc.

l  Physical and Chemical Information

Appearance

White or off-white solid

Solubility(25°C)

DMSO

45mg/ml

Ethanol

~5mg/ml

Water

Very slightly soluble

l  Biological Information

Biochem/Physiol  Actions

Betamethasone is a synthetic glucocorticoid with metabolic, immunosuppressive and anti-inflammatory activities. Betamethasone binds to specific intracellular glucocorticoid receptors and subsequently binds to DNA to modify gene. The synthesis of certain anti-inflammatory proteins is induced while the synthesis of certain inflammatory mediators is inhibited. As a result, there is an overall reduction in chronic inflammation and autoimmune reactions.

l  Storage

Storage temp.

-20°C

l  Precautions and Disclaimer

This product is for R&D use only, not for drug, household, or other uses.

l  References

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov

 

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