l General Information |
Product Name | Betamethasone |
General description | Betamethasone is a glucocorticoid steroid with anti-inflammatory and immunosuppressive properties. |
Synonym | NSC-39470; SCH-4831 |
Purity | ≥98.0%(HPLC) | CAS Number | 378-44-9 |
Formula | C22H29FO5 | Molecular Weight | 392.467 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | White or off-white solid |
Solubility(25°C) | DMSO | 45mg/ml |
Ethanol | ~5mg/ml |
Water | Very slightly soluble |
l Biological Information |
Biochem/Physiol
Actions | Betamethasone is a synthetic glucocorticoid with metabolic, immunosuppressive and anti-inflammatory activities. Betamethasone binds to specific intracellular glucocorticoid receptors and subsequently binds to DNA to modify gene. The synthesis of certain anti-inflammatory proteins is induced while the synthesis of certain inflammatory mediators is inhibited. As a result, there is an overall reduction in chronic inflammation and autoimmune reactions. |
l Storage |
Storage temp. | -20°C |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |