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Drospirenone

Product #: TS0584
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Details

l  General Information

Product Name

Drospirenone

General description

Drospirenone is a synthetic progestin that is an analog to spironolactone.

Synonym

ZK 3059

Purity

≥97.0%(HPLC)

CAS Number

67392-87-4

Formula

C24H30O3

Molecular Weight

366.501

Suitability

BioReagent, suitable for cell culture, etc.

l  Physical and Chemical Information

Appearance

White or off-white solid

Solubility(25°C)

DMSO

≥45mg/ml

Ethanol

~5mg/ml

Water

Very slight soluble

l  Biological Information

Biochem/Physiol  Actions

Drospirenone is a synthetic spironolactone analogue and progestin with progestational and anti-mineralocorticoid activity. Drospirenone binds to the progesterone receptor, the resulting complex becomes activated and binds to specific sites on DNA. This results in a suppression of LH activity and an inhibition of ovulation as well as an alteration in the cervical mucus and endometrium. This leads to an increased difficulty of sperm entry into the uterus and implantation. This drug is used in oral contraceptives.

l  Storage

Storage temp.

-20°C

l  Precautions and Disclaimer

This product is for R&D use only, not for drug, household, or other uses.

l  References

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov

 

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