l General Information |
Product Name | Felbamate |
General description | Felbamate is an anticonvulsant drug used in the treatment of epilepsy NMDAR antagonist. |
Synonym | ADD-03055; Felbatol; (3-carbamoyloxy-2-phenylpropyl) carbamate |
Purity | ≥98.0%(HPLC) | CAS Number | 25451-15-4 |
Formula | C11H14N2O4 | Molecular Weight | 238.243 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | White to white or light beige solid |
Solubility(25°C) | DMSO | ≥25mg/mL |
Ethanol | Very slight soluble |
Water | Very slight soluble |
l Biological Information |
Biochem/Physiol
Actions | Felbamate is a propanediol compound with anticonvulsant and antiepileptic properties. Although the exact mechanism of action is unknown, Felbamate may be an antagonist at the strychnine-insensitive glycine-recognition site of the N-methyl-D-aspartate (NMDA) receptor-ionophore complex, thereby blocking the effects of the excitatory amino acids, suppressing neuronal firing, and preventing seizure activity. Felbamate also has weak inhibitory effects on gamma-aminobutyric
acid (GABA) receptor binding sites which may contribute to its inhibitory effect on neuronal excitatory. |
l Storage |
Storage temp. | -20°C |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
