l General Information |
Product Name | Altretamine |
General description | Altretamine is an anti-neoplastic agent. |
Synonym | Hexamethylmelamine; NSC13875; ENT50852; 2-N,2-N,4-N,4-N,6-N,6-N-hexamethyl-1,3,5-triazine-2,4,6-triamine |
Purity | ≥98.0%(HPLC) | CAS Number | 645-05-6 |
Formula | C9H18N6 | Molecular Weight | 210.285 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | White or off-white solid |
Solubility(25°C) | DMSO | ~5mg/ml |
Ethanol | ≥15 mg/ml |
Water | Very slightly soluble |
l Biological Information |
Biochem/Physiol
Actions | Altretamine is a synthetic cytotoxic s-triazine derivative similar in structure to alkylating agent triethylenemelamin with antineoplastic activity. Although the precise mechanism by which altretamine exerts its cytotoxic effect is unknown, N demethylation of altretamine may produce reactive intermediates which covalently bind to DNA, resulting in DNA damage. |
l Storage |
Storage temp. | -20°C |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
