l General Information |
Product Name | Dacarbazine |
General description | Dacarbazine is a triazene derivative with antineoplastic activity. Dacarbazine alkylates and cross-s DNA during all phases of the cell cycle, resulting in disruption of DNA function, cell cycle arrest, and apoptosis used in the treatment of various cancers. |
Synonym | DTIC-Dome; 4-[(E)-dimethylaminodiazenyl]-1H-imidazole-5-carboxamide |
Purity | ≥98.0%(HPLC) | CAS Number | 4342-03-4 |
Formula | C6H10N6O | Molecular Weight | 182.187 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | White or Slightly Yellowish Solid |
Solubility(25°C) | DMSO | ~5mg/ml |
Ethanol | Very slightly soluble |
Water | Very slightly soluble |
l Biological Information |
Biochem/Physiol
Actions | Dacarbazine is a triazene derivative with antineoplastic activity. Dacarbazine alkylates and cross-s DNA during all phases of the cell cycle, resulting in disruption of DNA function, cell cycle arrest, and apoptosis. |
l Storage |
Storage temp. | -20°C |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
