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Imiquimod

Product #: TS0534
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Details

l  General Information

Product Name

Imiquimod

General description

Imiquimod is a novel synthetic agent with immune response modifying activity.

Synonym

R-837; S-26308; 1-(2-methylpropyl)imidazo[4,5-c]quinolin-4-amine

Purity

≥98.0%(HPLC)

CAS Number

99011-02-6

Formula

C14H16N4

Molecular Weight

240.31

Suitability

BioReagent, suitable for cell culture, etc.

l  Physical and Chemical Information

Appearance

Solid

Solubility(25°C)

DMSO

Slightly soluble

Ethanol

Insoluble

Water

Very slightly soluble

l  Biological Information

Biochem/Physiol  Actions

Imiquimod is a synthetic agent with immune response modifying activity. As an immune response modifier (IRM), imiquimod stimulates cytokine production, especially interferon production, and exhibits antitumor activity, particularly against cutaneous cancers. Imiquimod's proapoptotic activity appears to be related to Bcl-2 over in susceptible tumor cells.

l  Storage

Storage temp.

-20°C

l  Precautions and Disclaimer

This product is for R&D use only, not for drug, household, or other uses.

l  References

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov

 

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