l General Information |
Product Name | SL-327 |
General description | SL327 is a selective inhibitor for MEK1/2 with IC50 of 0.18 μM/ 0.22 μM, no activity towards Erk1, MKK3, MKK4, c-JUN, PKC, PKA, or CamKIIcapable of transport through the blood-brain barrier. |
Synonym | (Z)-3-amino-3-(4-aminophenyl)sulfanyl-2-[2-(trifluoromethyl)phenyl]prop-2-enenitrile |
Purity(HPLC) | ≥98%(Mixture of E & Z isomers) | CAS Number | 305350-87-2 |
Formula | C16H12F3N3S | Molecular Weight | 335.348 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | White to off-white solid |
Solubility(25°C) | DMSO | ≥45mg/ml |
Ethanol | ≥15mg/ml |
Water | Very slightly soluble |
l Storage |
Storage temp. | -20°C |
l Precautions and Disclaimer |
This product is for R&D use only, not
for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
