l General Information |
Product Name | Gonadorelin Acetate |
General description | Gonadorelin Acetate is another name for gonadotropin-releasing hormone (GnRH). It is a synthetic decapeptide prepared using solid phase peptide synthesis. |
Synonym | Glp-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2 |
Purity | ≥98.0%(HPLC) | CAS Number | 71447-49-9 |
Formula | C55H75N17O13 · xC2H4O2 | Molecular Weight | 1182.311(free base basis) |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | Solid |
l Biological Information |
Biochem/Physiol
Actions | Recombinant Gonadorelin is a synthetic luteinizing hormone releasing hormone (LHRH) identical to or similar to the endogenous hormone. Synthesized in and secreted by the hypothalamus, gonadorelin binds to transmembrane LHRH receptors on pituitary gonadotrophic cells, thereby stimulating synthesis and secretion of gonadotropins. Continuous administration of gonadorelin desensitizes the gonadotrophic cells, a negative feedback effect. This agent can be used in treatment of hypothalamic amenorrhea and evaluation of hypothalamic/pituitary function. |
l Storage |
Storage temp. | -20°C |
l Precautions and Disclaimer |
This product is for R&D use only, not
for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
