l General Information |
Product Name | Dabigatran (BIBR 953) |
General description | Dabigatran is a potent nonpeptide thrombin inhibitor. |
Synonym | 3-[[2-[(4-carbamimidoylanilino)methyl]-1-methylbenzimidazole-5-carbonyl]-pyridin-2-ylamino]propanoic acid |
Purity | ≥98.0%(HPLC) | CAS Number | 211914-51-1 |
Formula | C25H25N7O3 | Molecular Weight | 471.51 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | Solid |
Solubility(25℃) | DMSO | Very slightly soluble |
Ethanol | Very slightly soluble |
Water | ≥30mg/mL |
l Biological Information |
Biochem/Physiol
Actions | Dabigatran is an aromatic amide obtained by formal condensation of the carboxy group of 2-{[(4 carbamimidoylphenyl)amino]methyl}-1-methyl-1H-benzimidazole-5-carboxylic acid with the secondary amoino group of N pyridin-2-yl-beta-alanine. The active metabolite of the prodrug dabigatran etexilate, it acts as an anticoagulant which is used for the prevention of stroke and systemic embolism. It has a role as an anticoagulant, an EC 3.4.21.5 (thrombin) inhibitor and an EC 1.10.99.2 [ribosyldihydronicotinamide dehydrogenase (quinone)] inhibitor. |
l Storage |
Storage temp. | -20℃ |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
